About PreSens

Germany's PreSens, based on research activities that began in the 1980s, was founded in 1997 as a derivative of the University of Regensburg in Germany. PreSens has become one of the leading companies in the field of chemical optical sensor.

PreSens provides system

Measurement of oxygen in gases and liquids

Non invasive online pH, carbon dioxide, and oxygen measurement

Oxygen and pH sensors for disposable bioreactors

Micro oxygen and pH sensors

Biomass monitoring for process control in shaking bottles

Dissolved oxygen measurement for fermentation and bioreactor systems

Online oxygen and pH measurement in disposable products such as perforated boards and plastic bags

A two-dimensional mapping imaging solution for oxygen, pH, and carbon dioxide

The core of optical measurement technology is fluorescence analysis sensitive materials (fluorescence quenching principle)

Fluorescence response of indicator material excited by light pulses

Depending on the number of analyte molecules, the fluorescence signal undergoes a change and quenching

Signal changes can be measured using corresponding instruments

Non invasive measurement (non-invasive measurement)

No drilling or sampling: avoid oxygen entry and carbon dioxide emissions (accurate measurement)

Does not cause oxygen consumption

Non glass product probe, no risk of breakage

Signal measurement is independent of flow velocity

Note: Sensors have the advantages of small size, light weight, good electrical insulation, no electric sparks, safety, anti electromagnetic interference, high sensitivity, and easy to use communication skills to form telemetry networks

1. Oxygen meter (headspace oxygen measurement)

Single channel and multi-channel equipment for precise measurement of oxygen

PreSens has the perfect oxygen meter to meet any application needs. They can be used in conjunction with miniature oxygen sensors, nodes, flow cells, or immersion probes equipped with stainless steel shells. Portable or wall mounted systems equipped with display screens have enormous storage capacity and can be used independently of computers for a long time. Our small desktop oxygen meter - which can be used as a single channel or multi-channel device - is controlled by a personal computer through the PreSens Measurement Studio 2 software. This software allows for simultaneous control of multiple instruments. The trace oxygen analyzer provides a measurement range of 1 ppb to 100% oxygen. Due to the principle of fiber optic measurement, such instruments can even be used for measurement work in hazardous areas. Here, you will find the ideal oxygen meter to meet your needs!

Handheld Microx 4 and Fibox 4 devices are ideal tools for on-site research

It can be used for the determination of gaseous oxygen or dissolved oxygen. By combining different types of oxygen sensors, such equipment can be used for water quality assessment, respiratory measurement, or tissue measurement. This type of oxygen meter is suitable for any place that requires precise oxygen measurement. Due to its splashproof performance and sturdy casing, this type of oxygen meter can be used in harsh environments. Special energy settings for long-term measurement, with almost unlimited storage capacity or graphical display of your measurement results, allowing for long-term and comfortable use independently of the computer.

OXY-1 ST (trace) OXY-1 SMA (trace)

This series of ultra small oxygen meters are powered by USB and controlled by PreSens Measurement Studio 2 software. It can be used with ST/SMA compatible sensor nodes, immersion probes, flow cells, and micro sensors. This series of devices is suitable for almost any field. This device has temperature, pressure, and salinity compensation functions. The Oxy-1 trace series can detect trace oxygen, with a measurement range of 1 ppb to 100%

2. Non invasive oxygen sensor

A non-invasive optical oxygen sensor for measuring dissolved oxygen and gaseous oxygen. They are fixed on the inner surface of transparent glass or plastic materials. Then, the oxygen concentration can be measured externally through the container wall in a non-contact and non-destructive manner. And provide sensor coatings suitable for different concentration ranges.

Online monitoring without sampling

Suitable for micro upgrade to production level

Non contact and non-destructive measurement

Pre calibrated, ready to use

Integrated into disposable items

Suitable for bags and disposable bioreactors

Suitable for transparent containers such as PET bottles and glass bottles

Non Immersion Chip Type - Characteristics of Oxygen Sensors

1. Online detection

2. Non immersion measurement

3. Dissolved oxygen range 1ppb-45ppm

4. No need to consume oxygen

5. Signal not limited by flow rate

6. Can measure dissolved oxygen and oxygen in air using patch based measurement

Application field:

1. Pharmaceutical Industry: Oxygen Measurement in Drug Bags

2. Food and Beverage Industry: Measurement of Oxygen Content in PET Bottles

3. Research industries such as biopharmaceuticals

3. Micro oxygen sensor

Sensor tip thinner than hair (<50 µ m) - on-site measurement

Needle type miniature oxygen sensor NTH

Implantable miniature oxygen sensor IMP (installed in customer's own shell, steel pipe)

Micro profile measurement sensor PM (micro operation)

Micro Oxygen Sensor NFSG with Fixed Sensor Ends

Micro oxygen sensors are miniaturized chemical optical oxygen sensors designed for all research and packaging applications that require small end size (<50 µ m) and fast response time (t90<3sec.). The optical micro oxygen sensor is based on 230 µ m quartz fiber and can provide sensor tip diameters ranging from<50 µ m to 230 µ m. Micro oxygen sensors are installed in different shells (needle shell, implantable, micro profile measurement) and provide unique tools for investigating systems that require micro invasive and small sensors.

The oxygen inside the packaging can cause certain products to oxidize and deteriorate. Therefore, measuring the oxygen content in packaging or drug bottles is crucial for ensuring filling quality and long-term storage stability. Our micro invasive needle type micro oxygen sensor provides a simple tool for determining residual oxygen in headspace and liquid.

Micro oxygen sensors measure the oxygen content in various volume chambers of tissue engineering structures. For this purpose, sensors as thin as hair are inserted into the structure and then the oxygen content is measured online. Using this method, oxygen partial pressure can be measured with high local resolution and correlated with the quality of structural tissue (composition of extracellular matrix).

For fields such as small headspace and pharmaceutical packaging, it can conveniently, accurately, and quickly measure the content of gas components inside packaging such as drugs and food.

Oxygen flow tank

Chemical optical oxygen sensors integrated into plastic or metal flow cells (FTCs) allow non-invasive online monitoring in infusion systems or production lines. The sensor can be fixed on a color coding rod, which can be attached to flow cells of different sizes and shapes, or fixed on an optical exchange window installed inside the flow cell. Polymer optical fibers connect the sensors in the flow cell to the corresponding oxygen meter. Plastic FTC is made of polycarbonate, while metal flow cells can be cleaned in situ or steam sterilized.

Oxygen probes in research and industrial fields

PreSens optical oxygen probes can provide various designs to meet the needs of most different application fields, such as industrial process control or environmental research. This type of equipment measures gaseous oxygen and dissolved oxygen, and can be used in different measurement ranges from 0.5 ppmv to 100% oxygen. This type of probe uses an advanced stainless steel casing, which is resistant to harsh conditions and can be safely applied in fields such as food production and filling or biotechnology processes. After connecting fiber optic probes to our various oxygen meters, they can even be installed in hazardous areas. The integrated OXYPro series is directly connected to the control unit, making it an ideal solution for process monitoring.

}Different measurement ranges from 0.5 ppmv to 100% oxygen

}Probes can be used for online measurement in the industrial field

}Directly connected to the controller

}High temperature and high pressure sterilization, in situ sterilization (SIP, 130 ° C1.5 atm), and in situ cleaning (CIP, 80 ° C, 2% sodium hydroxide)

}The probe can be installed in hazardous areas

}Small size to meet environmental application requirements

}Unpolarization

}No need to clean the film

}Withstand voltage

The oxygen probe used for online measurement is designed specifically for harsh conditions such as high pressure or oil/water mixtures. This type of system provides high precision, does not contain membranes and electrolytes, and is almost maintenance free. This type of sensor is resistant to high temperature and pressure, steam sterilization, and in situ cleaning.

Low concentrations of oxygen can also affect shelf life and the taste of certain beverages. The PreSens trace oxygen sensor has extremely low detection limits and excellent accuracy, ensuring the quality of oxygen sensitive products such as beer, wine, and soft drinks. Compared to standard electrodes, optical sensors have ultra fast response time and are extremely easy to maintain.

This series of compact probes integrates the electro-optic module with the sensor in a stainless steel casing. This series of sensors is integrated into a detachable cap and can be easily replaced if necessary. The Oxy base series probes are extremely sturdy and ideal for fields such as oxygen monitoring in fish farms.

VisiSens ™ Oxygen imaging system

Record the spatial and temporal distribution of oxygen

Fluorescent chemical optical sensing film combined with VisiSens ™ Imaging technology can perform non-invasive oxygen distribution mapping within heterogeneous samples. The fluorescent sensing film is directly attached to the surface of the sample or placed in a transparent container made of glass or plastic material. The sensing film is available in various sizes and can be cut as needed to convert oxygen content into optical signals. Utilizing VisiSens ™ Imaging equipment that records the spatial and temporal responses of two-dimensional sensors in a non-contact manner.

2D reading

Non contact direct sensing or transparent wall sensing to visually display spatial and temporal gradient changes

An image contains multiple measurement points

The key to cellular metabolism depends on the level of local oxygen supply. Especially in two-dimensional and three-dimensional cell cultures or engineered tissues, cells located in diffusion restricted areas (such as scaffolds or spheroids) may be at low oxygen levels and undergo pH changes. Non invasive continuous two-dimensional mapping can be performed directly in the incubator under growth conditions, and can visually display the two-dimensional distribution of analytes in living samples.

Main applications

Online detection of oxygen and pH values in the perfusion system

Detecting the concentration of oxygen in the brewing and beverage industry (oxygen affects shelf life and taste)

Detection of oxygen and pH values in the bypass of an integrated bioreactor (regulating the oxygen content and pH value of the bioreactor)

Packaging and quality control (oxygen content in packaging or bottles affects filling quality and long-term storage stability)

Precise insertion of small tips into cellular tissue, determination of oxygen and pH within the structure

Measure the oxygen and pH values of sediment and biological profiles layer by layer

Measure the pH values in plants and animals, as well as in medical tumor environments (with strong anti-interference ability and no impact on biological activity)

Biotechnology and Pharmaceutical Industry Process Control

(High temperature and high pressure resistance, steam sterilization, and in situ cleaning, without membrane and electrolyte, maintenance free)

Monitoring the ventilation and oxygen content in the soil

Online detection of oxygen and pH values in the perfusion system

Detecting the concentration of oxygen in the brewing and beverage industry (oxygen affects shelf life and taste)

Detection of oxygen and pH values in the bypass of an integrated bioreactor (regulating the oxygen content and pH value of the bioreactor)